Monte San Giusto lies amid the valleys where the Cremone and the Ete Morto flow, in a panoramic position facing the sea. Here stands one of the most important Renaissance buildings of Marche together with Palazzo Ducale in Urbino: Palazzo Bonafede, today site of the Museo di Monte San Giusto. Not far from here stands the church of Santa Maria in Telusiano (or della Pietà) founded in the fourteenth century but restored in the sixteenth, and housing a Crucifixion by Lorenzo Lotto in its original frame. The work, commissioned to Lotto by Nicolò Bonafede, bishop of Chiusi and official of the Roman court, includes its patron: marked by a grandiose drama in the depiction of the Crucifixion, the composition also includes a portrait of Bonafede kneeling and contemplating the fainting of Mary. The picture is a representation of suffering in which the tragedy is never desperation and nor is the truth displayed as realism.